From: LFrank [e-mail address redacted] Sent: Thursday, April 17, 2014 10:52 AM To: myriad-mayo_2014 Subject: grammar Dear Sir or Madam, This is just to note the USPTO’s being caught up in the latest grammatical error to sweep the nation. This is the run-on sentence of the following structure: [Sentence], however, [second sentence]. When government agencies err this way, it validates the erroneous grammar and suggests that this is actually good grammar. Please stop. It is better, easy, and correct to write the above as [Sentence]. [Second sentence]. The sentence I refer to is in your guidance memorandum titled Guidance For Determining Subject Matter Eligibility Of Claims Reciting Or Involving Laws of Nature, Natural Phenomena, & Natural Products and reads as follows: “The leaves of the Amazonian cherry tree contain a chemical that is useful in treating breast cancer, however, to be effective, a patient must eat 30 pounds of the leaves per day for at least four weeks.” This is a classic, grammatically incorrect, run-on sentence. It would be correct, and easy, to write it as: “The leaves of the Amazonian cherry tree contain a chemical that is useful in treating breast cancer. To be effective, however, a patient must eat 30 pounds of the leaves per day for at least four weeks.” I understand that this email will have no impact whatsoever. Sincerely, Lawrence Frank Lawrence H. Frank Resek, Liang & Frank LLP 68 Jay Street, Suite 201 Brooklyn, NY 11201 (718) 701-8765 (work) (917) 882-3553 (mobile) www.rlfpatentlaw.com